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Angiogenesis is a complex process that involves multiple cellular events. In addition to receiving inputs from a range of stimulatory and inhibitory factors, endothelial cells undergoing



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A Functional Yeast Survival Screen of Tumor-Derived cDNA

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Methods. A total protein extract, Myogel, was formulated from myoma. The protein contents of Myogel were characterized and its composition and properties compared with a commercial mouse Matrigel®.

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The number of midbody derivatives in a cell may be modulated by modulating autophagy induced by NBR1. Exemplary methods include modulating the amount or activity of NBR1 in the cell, potentiating or inhibiting binding between NBR1 and Cep55 in the cell, or modulating the amount of Cep55 in the cell.

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The control shRNA sequence was obtained from the “Open Biosystems pGIPZ shRNAmir library” situated at University College London. 5 To confirm the functioning of the shRNA, shRNA expression plasmids were co-transfected into HEK293 cells in the absence or presence of a commercially available ZNF683/HOBIT expression plasmid (ORF of ZNF683, transcript variant 1, in pEnter, with C-terminal …

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Microglia are the intrinsic immune sentinels of the central nervous system. Their activation restricts tissue injury and pathogen spread, but in some settings, including viral infection, this response can contribute to cell death and disease.

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